Familial Aggregation: Sorting Susceptibility From Shared Environment
نویسندگان
چکیده
منابع مشابه
Familial Aggregation of Stroke
Stroke is the second leading cause of death worldwide, and the leading cause of acquired disability in adults in most regions. Fifteen million people worldwide suffer a stroke each year with devastating effects; one third of these individuals die and another one third remains permanently disabled. However, there is a considerable additional unreported asymptomatic cerebrovascular disease. Accor...
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Likelihood calculation for pedigrees is complicated and often time-consuming. Testing correlation structures due to familial aggregation is therefore a preliminary procedure. A score statistic is given to check correlations between relatives of randomly chosen pedigrees. This statistic can be used for quantitative and dichotomous data. For both data types, the distribution of the statistic unde...
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Recent studies on the pathogenesis of tuberculosis have. been directed toward a better appreciation of the multiplicity of factors superimposed on the sine qua non of exposure to the tubercle bacillus. The question of hereditary influence-long in the ascendancy in the pre-Koch era-has again come to the fore. The striking demonstration of the role of genetic factors in experimental infection has...
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Absolute pitch (AP) is a behavioral trait that is defined as the ability to identify the pitch of tones in the absence of a reference pitch. AP is an ideal phenotype for investigation of gene and environment interactions in the development of complex human behaviors. Individuals who score exceptionally well on formalized auditory tests of pitch perception are designated as "AP-1." As described ...
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ژورنال
عنوان ژورنال: Journal of the National Cancer Institute
سال: 2000
ISSN: 1460-2105
DOI: 10.1093/jnci/92.14.1114